AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

08 Oct - 14 Oct	KLM
31 Oct - 07 Nov	Air Europa
01 Oct - 08 Oct	KLM
01 Oct - 09 Oct	KLM
02 Oct - 17 Oct	KLM
08 Oct - 13 Oct	KLM
16 Oct - 25 Oct	Air Europa
15 Oct - 19 Nov	Air Europa
16 Oct - 19 Nov	Air Europa
16 Oct - 24 Nov	Air Europa
02 Oct - 05 Oct	KLM
04 Oct - 05 Oct	KLM
03 Oct - 06 Oct	KLM
01 Oct - 04 Oct	KLM
25 Oct - 26 Nov	Air Europa
15 Oct - 19 Nov	Turkish Airlines	direct
16 Oct - 19 Nov	Turkish Airlines	direct
16 Oct - 24 Nov	Turkish Airlines	direct
25 Oct - 26 Nov	Turkish Airlines	direct
31 Oct - 07 Nov	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo

Cheapest return flights from Istanbul to Sao Paulo in October from $808

Return flights