AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

28 Oct - 06 Nov	KLM
29 Oct - 02 Nov	KLM
29 Oct - 05 Nov	KLM
29 Oct - 16 Nov	KLM
23 Oct - 29 Oct	Air Europa
25 Oct - 09 Nov	Air Europa
23 Oct - 28 Oct	KLM
31 Oct - 16 Nov	Air Europa
24 Oct - 31 Oct	Air Europa
25 Oct - 12 Nov	Air Europa
25 Oct - 31 Oct	Air Europa
25 Oct - 02 Nov	Air Europa
31 Oct - 04 Nov	Air Europa
27 Oct - 09 Nov	KLM
27 Oct - 31 Oct	KLM
25 Oct - 31 Oct	Turkish Airlines	direct
27 Oct - 31 Oct	Turkish Airlines	direct
26 Oct - 31 Oct	Turkish Airlines	direct
23 Oct - 28 Oct	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Sao Paulo in October from $1183

Return flights