AirHint found the following cheapest return flights from Istanbul (IST) to Sao Paulo (GRU) in November 2025 (see full year).

Return flights

08 Nov - 21 Nov	KLM
17 Nov - 25 Nov	KLM
10 Nov - 18 Nov	KLM
11 Nov - 16 Nov	KLM
24 Nov - 01 Dec	KLM
25 Nov - 02 Dec	KLM
10 Nov - 25 Nov	KLM
14 Nov - 16 Nov	KLM
04 Nov - 11 Nov	KLM
14 Nov - 25 Nov	KLM
16 Nov - 27 Nov	KLM
14 Nov - 23 Nov	KLM
27 Nov - 01 Dec	KLM
07 Nov - 07 Dec	KLM
25 Nov - 06 Dec	KLM
30 Nov - 07 Dec	KLM
25 Nov - 08 Dec	KLM
27 Nov - 14 Dec	Qatar Airways
03 Nov - 01 Dec	British Airways
27 Nov - 14 Dec	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Sao Paulo in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Sao Paulo in November from $791

Return flights