Cheapest return flights from Istanbul to Madrid in October from $235

Best time to book flights for Istanbul (IST) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Istanbul (IST) to Madrid (MAD) in October 2025 (see full year).

Return flights

21 Oct - 28 Oct Wizz Air UK
03 Oct - 04 Nov Wizz Air UK
20 Oct - 24 Oct Wizz Air UK
01 Oct - 07 Oct Pegasus Airlines
03 Oct - 04 Nov Pegasus Airlines direct
01 Oct - 05 Oct Pegasus Airlines
17 Oct - 19 Oct AJet
29 Oct - 02 Nov Aegean Airlines
01 Oct - 09 Oct Pegasus Airlines
16 Oct - 19 Oct Wizz Air
08 Oct - 12 Oct Pegasus Airlines direct
29 Oct - 02 Nov Air Europa direct
11 Oct - 18 Oct Pegasus Airlines
24 Oct - 28 Oct Pegasus Airlines direct

Also check the deals for one-way flights from Istanbul to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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