Cheapest return flights from Istanbul to Madrid in September from $239

Best time to book flights for Istanbul (IST) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest return flights from Istanbul (IST) to Madrid (MAD) in September 2025 (see full year).

Return flights

19 Sep - 26 Sep AJet
17 Sep - 24 Sep AJet
24 Sep - 29 Sep Pegasus Airlines
24 Sep - 28 Sep Pegasus Airlines
11 Sep - 17 Sep Pegasus Airlines
19 Sep - 21 Sep AJet
22 Sep - 27 Sep KLM
19 Sep - 28 Sep AJet
11 Sep - 18 Sep Pegasus Airlines
26 Sep - 28 Sep AJet
23 Sep - 09 Oct Wizz Air UK
27 Sep - 02 Oct Pegasus Airlines
23 Sep - 09 Oct Pegasus Airlines direct
27 Sep - 02 Oct Air Europa direct

Also check the deals for one-way flights from Istanbul to Madrid in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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