AirHint found the following cheapest return flights from Istanbul (IST) to Milano (MXP) in October 2025 (see full year).

Return flights

02 Oct - 05 Oct	Turkish Airlines
02 Oct - 09 Oct	Turkish Airlines
04 Oct - 09 Oct	Turkish Airlines
01 Oct - 05 Oct	Wizz Air
10 Oct - 12 Oct	Pegasus Airlines
09 Oct - 12 Oct	Wizz Air UK
03 Oct - 05 Oct	Wizz Air UK
03 Oct - 09 Oct	Wizz Air UK
07 Oct - 14 Oct	Turkish Airlines
02 Oct - 07 Oct	Turkish Airlines
31 Oct - 04 Nov	AJet
29 Oct - 02 Nov	AJet
18 Oct - 04 Nov	Fly One
18 Oct - 01 Nov	Fly One
25 Oct - 04 Nov	Fly One
29 Oct - 02 Nov	Turkish Airlines	direct
28 Oct - 02 Nov	Turkish Airlines	direct
23 Oct - 04 Nov	Vueling Airlines
25 Oct - 11 Nov	Fly One
25 Oct - 01 Nov	Fly One

Also check the deals for one-way flights from Istanbul to Milano in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Milano

Cheap car rent in Milano

Cheapest return flights from Istanbul to Milano in October from $133

Return flights