AirHint found the following cheapest return flights from Istanbul (IST) to Prague (PRG) in April 2026 (see full year).

Return flights

04 Apr - 07 Apr	Air Serbia
20 Apr - 24 Apr	Air Serbia
18 Apr - 20 Apr	Air Serbia
17 Apr - 20 Apr	Air Serbia
18 Apr - 25 Apr	Air Serbia
13 Apr - 17 Apr	Air Serbia
30 Apr - 02 May	Air Serbia
21 Apr - 24 Apr	Air Serbia
20 Apr - 10 May	SKY express
25 Apr - 10 May	SKY express
24 Apr - 27 Apr	SKY express
08 Apr - 11 Apr	Wizz Air UK
11 Apr - 18 Apr	Scandinavian Airlines
30 Apr - 03 May	Air Serbia
20 Apr - 03 May	SKY express
25 Apr - 03 May	SKY express
30 Apr - 02 May	Turkish Airlines	direct
17 Apr - 03 May	SKY express
22 Apr - 10 May	Fly One
13 Apr - 03 May	Fly One

Also check the deals for one-way flights from Istanbul to Prague in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Prague in April from $207

Return flights