Cheapest return flights from Istanbul to Prague in September from $166

AirHint found the following cheapest return flights from Istanbul (IST) to Prague (PRG) in September 2025 (see full year).

Return flights

29 Sep - 03 Oct Wizz Air UK
04 Sep - 10 Sep Pegasus Airlines direct
14 Sep - 19 Sep Pegasus Airlines direct
20 Sep - 27 Sep Pegasus Airlines direct
24 Sep - 26 Sep Pegasus Airlines direct
29 Sep - 03 Oct Pegasus Airlines direct
11 Sep - 17 Sep Pegasus Airlines direct
11 Sep - 16 Sep Pegasus Airlines direct
11 Sep - 19 Sep Pegasus Airlines direct
11 Sep - 18 Sep Pegasus Airlines direct
19 Sep - 27 Sep Pegasus Airlines direct
22 Sep - 27 Sep Wizz Air UK
21 Sep - 03 Oct Pegasus Airlines direct

Also check the deals for one-way flights from Istanbul to Prague in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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