Cheapest return flights from Istanbul to Prague in September from $159

Best time to book flights for Istanbul (IST) to Prague (PRG) flights at AirHint

AirHint found the following cheapest return flights from Istanbul (IST) to Prague (PRG) in September 2025 (see full year).

Return flights

20 Sep - 23 Sep Pegasus Airlines direct
01 Sep - 06 Sep Pegasus Airlines direct
06 Sep - 14 Sep Pegasus Airlines direct
02 Sep - 06 Sep Pegasus Airlines direct
01 Sep - 09 Sep Pegasus Airlines direct
08 Sep - 11 Sep Pegasus Airlines direct
19 Sep - 27 Sep Pegasus Airlines direct
08 Sep - 12 Sep Pegasus Airlines direct
22 Sep - 27 Sep Pegasus Airlines direct
01 Sep - 05 Sep Pegasus Airlines direct
30 Sep - 12 Oct Pegasus Airlines direct

Also check the deals for one-way flights from Istanbul to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague