AirHint found the following cheapest return flights from Istanbul (IST) to Samarkand (SKD) in September 2025 (see full year).

Return flights

29 Sep - 06 Oct	Centrum Air	direct
04 Sep - 11 Sep	Centrum Air	direct
01 Sep - 08 Sep	Centrum Air	direct
15 Sep - 18 Sep	Centrum Air	direct
11 Sep - 18 Sep	Centrum Air	direct
01 Sep - 07 Sep	AZAL
01 Sep - 26 Oct	AZAL
09 Sep - 20 Oct	AZAL
10 Sep - 17 Sep	Turkish Airlines	direct
01 Sep - 26 Oct	Turkish Airlines	direct
18 Sep - 23 Sep	Centrum Air
13 Sep - 21 Sep	AZAL
01 Sep - 07 Sep	Turkish Airlines	direct
13 Sep - 21 Sep	Turkish Airlines	direct
09 Sep - 20 Oct	Turkish Airlines	direct

Also check the deals for one-way flights from Istanbul to Samarkand in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Istanbul to Samarkand in September from $302

Return flights