AirHint found the following cheapest return flights from Osaka (ITM) to Istanbul (IST) in September 2025 (see full year).

Return flights

28 Sep - 02 Oct	Japan Airlines
28 Sep - 08 Oct	ANA
23 Sep - 29 Sep	ANA
23 Sep - 01 Oct	ANA
03 Sep - 08 Sep	Turkish Airlines
01 Sep - 10 Sep	Japan Airlines
01 Sep - 08 Sep	Japan Airlines
19 Sep - 24 Sep	ANA
19 Sep - 29 Sep	ANA
21 Sep - 29 Sep	ANA
05 Sep - 10 Sep	ANA
05 Sep - 17 Sep	ANA
09 Sep - 16 Sep	Japan Airlines
29 Sep - 02 Oct	ANA
25 Sep - 01 Oct	ANA
27 Sep - 04 Oct	Turkish Airlines

Also check the deals for one-way flights from Osaka to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Osaka to Istanbul in September from $1240

Return flights