AirHint found the following cheapest return flights from Osaka (ITM) to Madrid (MAD) in May 2026 (see full year).

Return flights

12 May - 03 Jun	Japan Airlines
12 May - 21 May	Japan Airlines
14 May - 21 May	Japan Airlines
11 May - 26 May	Japan Airlines
20 May - 02 Jun	Lufthansa
13 May - 17 Jun	Lufthansa
11 May - 29 May	Lufthansa
05 May - 15 May	Japan Airlines
04 May - 11 May	Lufthansa
16 May - 23 May	Lufthansa
23 May - 28 May	Lufthansa
01 May - 05 May	Japan Airlines

Also check the deals for one-way flights from Osaka to Madrid in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Osaka to Madrid in May from $1288

Return flights