AirHint found the following cheapest return flights from Jacksonville (JAX) to Santiago (SCL) in April 2026 (see full year).
Return flights
| 25 Apr - 02 May | Frontier Airlines | ||
| 26 Apr - 01 May | Frontier Airlines | ||
| 26 Apr - 10 May | Frontier Airlines | ||
| 14 Apr - 21 Apr | Breeze Airways |
Also check the deals for one-way flights from Jacksonville to Santiago in April.
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