AirHint found the following cheapest return flights from Johannesburg (JNB) to Istanbul (IST) in September 2025 (see full year).

Return flights

22 Sep - 29 Sep	KLM
29 Sep - 06 Oct	KLM
18 Sep - 22 Sep	KLM
24 Sep - 29 Sep	KLM
25 Sep - 01 Oct	KLM
29 Sep - 04 Oct	KLM
21 Sep - 01 Oct	KLM
20 Sep - 28 Sep	KLM
24 Sep - 28 Sep	KLM
21 Sep - 28 Sep	KLM
19 Sep - 24 Sep	Etihad Airways
19 Sep - 02 Oct	Etihad Airways
20 Sep - 05 Oct	Etihad Airways
30 Sep - 05 Oct	Etihad Airways
25 Sep - 05 Oct	Etihad Airways
25 Sep - 08 Oct	Ethiopian Airlines
26 Sep - 04 Oct	KLM
21 Sep - 26 Sep	KLM
24 Sep - 29 Sep	Turkish Airlines	direct
22 Sep - 29 Sep	Turkish Airlines	direct

Also check the deals for one-way flights from Johannesburg to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Johannesburg to Istanbul in September from $576

Return flights