AirHint found the following cheapest return flights from Santorini (Thira) (JTR) to Istanbul (IST) in September 2025 (see full year).

Return flights

21 Sep - 24 Sep	SKY express
21 Sep - 04 Oct	SKY express
21 Sep - 06 Oct	SKY express
28 Sep - 13 Oct	SKY express
28 Sep - 14 Oct	SKY express
28 Sep - 04 Oct	SKY express
28 Sep - 06 Oct	SKY express
28 Sep - 17 Oct	SKY express
09 Sep - 16 Sep	Ryanair
27 Sep - 30 Sep	Aegean Airlines
09 Sep - 13 Sep	Ryanair
21 Sep - 30 Sep	SKY express
21 Sep - 25 Sep	SKY express
28 Sep - 30 Sep	SKY express
21 Sep - 10 Oct	SKY express
21 Sep - 01 Oct	SKY express
21 Sep - 07 Oct	SKY express
14 Sep - 24 Sep	SKY express
14 Sep - 16 Sep	SKY express
14 Sep - 30 Sep	SKY express

Also check the deals for one-way flights from Santorini (Thira) to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santorini (Thira) to Istanbul in September from $283

Return flights