AirHint found the following cheapest return flights from Karachi (KHI) to Istanbul (IST) in September 2025 (see full year).

Return flights

18 Sep - 30 Sep	SalamAir
07 Sep - 20 Sep	Pegasus Airlines
06 Sep - 16 Sep	Pegasus Airlines
30 Sep - 07 Oct	Jazeera Airways
21 Sep - 28 Sep	SalamAir
20 Sep - 27 Sep	SalamAir
23 Sep - 30 Sep	Jazeera Airways
20 Sep - 04 Oct	Etihad Airways
13 Sep - 27 Sep	Etihad Airways
14 Sep - 23 Sep	Etihad Airways
26 Sep - 03 Oct	SalamAir
22 Sep - 02 Oct	Etihad Airways
29 Sep - 06 Oct	SalamAir
17 Sep - 24 Sep	SalamAir
12 Sep - 22 Sep	Etihad Airways
23 Sep - 05 Oct	Etihad Airways
20 Sep - 03 Oct	Etihad Airways
26 Sep - 07 Oct	Etihad Airways
25 Sep - 02 Oct	Etihad Airways
27 Sep - 04 Oct	Etihad Airways

Also check the deals for one-way flights from Karachi to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Karachi to Istanbul in September from $305

Return flights