AirHint found the following cheapest return flights from Los Angeles (LAX) to Panama City (PTY) in December 2025 (see full year).

Return flights

31 Dec - 30 Jan	Spirit Airlines
07 Dec - 11 Dec	Avianca
03 Dec - 08 Dec	Avianca
01 Dec - 08 Dec	Avianca
10 Dec - 13 Dec	Avianca
12 Dec - 14 Dec	Spirit Airlines
03 Dec - 06 Jan	Frontier Airlines
24 Dec - 31 Dec	Copa	direct
31 Dec - 30 Jan	Copa	direct
26 Dec - 08 Jan	Copa	direct
10 Dec - 13 Dec	Copa	direct
07 Dec - 11 Dec	Copa	direct
12 Dec - 14 Dec	Copa	direct
15 Dec - 29 Dec	Frontier Airlines
26 Dec - 07 Jan	Copa	direct
26 Dec - 09 Jan	Copa	direct
25 Dec - 01 Jan	Copa	direct
30 Dec - 06 Jan	Copa	direct
26 Dec - 02 Jan	Alaska Airlines
19 Dec - 13 Jan	Frontier Airlines

Also check the deals for one-way flights from Los Angeles to Panama City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Los Angeles to Panama City in December from $536

Return flights