AirHint found the following cheapest return flights from London (LCY) to Santiago (SCL) in September 2025 (see full year).

Return flights

15 Sep - 28 Sep	Delta
24 Sep - 01 Oct	SWISS
15 Sep - 30 Sep	Delta
10 Sep - 17 Sep	ITA Airways
17 Sep - 15 Oct	ITA Airways
22 Sep - 01 Oct	SWISS
11 Sep - 25 Sep	ITA Airways
11 Sep - 01 Oct	ITA Airways
08 Sep - 18 Sep	ITA Airways
16 Sep - 01 Oct	ITA Airways
16 Sep - 30 Sep	ITA Airways
15 Sep - 20 Sep	Delta
12 Sep - 17 Sep	ITA Airways
11 Sep - 16 Sep	ITA Airways
19 Sep - 05 Oct	Delta
15 Sep - 29 Sep	ITA Airways
30 Sep - 05 Oct	ITA Airways
12 Sep - 01 Oct	KLM
13 Sep - 04 Oct	KLM
27 Sep - 18 Oct	KLM

Also check the deals for one-way flights from London to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in September from $1298

Return flights