AirHint found the following cheapest return flights from London (LHR) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

30 Sep - 13 Oct	Virgin Atlantic
25 Sep - 29 Sep	Air Canada
19 Sep - 10 Oct	Avianca
24 Sep - 29 Sep	Virgin Atlantic
26 Sep - 12 Oct	Vueling Airlines
22 Sep - 29 Sep	Air Canada
29 Sep - 06 Oct	Vueling Airlines
29 Sep - 10 Oct	Virgin Atlantic
20 Sep - 01 Oct	Avianca
19 Sep - 30 Sep	Avianca
25 Sep - 02 Oct	Avianca
21 Sep - 05 Oct	Avianca
28 Sep - 03 Oct	Avianca
22 Sep - 28 Sep	Avianca
20 Sep - 04 Oct	Avianca
19 Sep - 23 Sep	Air Canada
21 Sep - 25 Sep	Avianca
19 Sep - 22 Sep	Avianca
21 Sep - 22 Sep	Avianca
19 Sep - 21 Sep	Avianca

Also check the deals for one-way flights from London to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Rio Negro in September from $916

Return flights