AirHint found the following cheapest return flights from London (LHR) to Santiago (SCL) in October 2025 (see full year).

Return flights

29 Oct - 14 Nov	Avianca
14 Oct - 21 Oct	Vueling Airlines
13 Oct - 27 Oct	Avianca
05 Oct - 23 Oct	Avianca
29 Oct - 20 Nov	TAP
21 Oct - 28 Oct	Avianca
07 Oct - 14 Oct	Avianca
27 Oct - 11 Nov	Air Canada
27 Oct - 04 Nov	Air Canada
05 Oct - 19 Oct	Avianca
06 Oct - 30 Oct	Air France
29 Oct - 12 Nov	Air Canada
09 Oct - 16 Oct	Avianca
31 Oct - 15 Nov	Air Canada
23 Oct - 14 Nov	Avianca
26 Oct - 10 Nov	Air Canada
26 Oct - 03 Nov	Air Canada
26 Oct - 04 Nov	Air Canada
19 Oct - 26 Oct	Avianca
18 Oct - 27 Oct	Avianca

Also check the deals for one-way flights from London to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in October from $1064

Return flights