AirHint found the following cheapest return flights from London (LHR) to Santiago (SCL) in October 2025 (see full year).

Return flights

29 Oct - 20 Nov	Air Canada
28 Oct - 06 Nov	Air Canada
28 Oct - 04 Nov	Air Canada
30 Oct - 20 Nov	Brussels Airlines
27 Oct - 06 Nov	Air Canada
27 Oct - 25 Nov	Brussels Airlines
27 Oct - 05 Nov	Air Canada
30 Oct - 10 Nov	Brussels Airlines
27 Oct - 07 Nov	Brussels Airlines
27 Oct - 04 Nov	Air Canada
14 Oct - 21 Oct	Delta
15 Oct - 22 Oct	Delta
14 Oct - 22 Oct	Delta
16 Oct - 23 Oct	Delta
23 Oct - 30 Oct	Delta
27 Oct - 31 Oct	Brussels Airlines
28 Oct - 30 Oct	Delta
22 Oct - 26 Oct	Delta
18 Oct - 23 Oct	Iberia
19 Oct - 31 Oct	British Airways

Also check the deals for one-way flights from London to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in October from $969

Return flights