AirHint found the following cheapest return flights from Lisbon (LIS) to Istanbul (IST) in December 2025 (see full year).

Return flights

09 Dec - 12 Dec	Air Europa
12 Dec - 14 Dec	Air Europa
10 Dec - 14 Dec	Air Europa
11 Dec - 14 Dec	Air Europa
01 Dec - 03 Dec	Air Europa
04 Dec - 10 Dec	Ryanair
01 Dec - 09 Dec	Air Europa
11 Dec - 15 Dec	Air Europa
05 Dec - 10 Dec	SKY express
06 Dec - 10 Dec	Ryanair
26 Dec - 28 Jan	Aegean Airlines
01 Dec - 02 Jan	easyJet
12 Dec - 02 Jan	Air Europa
17 Dec - 03 Jan	Pegasus Airlines
18 Dec - 03 Jan	Aegean Airlines
28 Dec - 04 Jan	Pegasus Airlines
28 Dec - 02 Jan	SKY express
31 Dec - 04 Jan	Pegasus Airlines
27 Dec - 02 Jan	Aegean Airlines
27 Dec - 04 Jan	Pegasus Airlines

Also check the deals for one-way flights from Lisbon to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Istanbul in December from $107

Return flights