AirHint found the following cheapest return flights from Lisbon (LIS) to Istanbul (IST) in September 2025 (see full year).

Return flights

17 Sep - 23 Sep	easyJet
17 Sep - 22 Sep	easyJet
12 Sep - 23 Sep	easyJet
24 Sep - 29 Sep	Ryanair
30 Sep - 06 Oct	easyJet
18 Sep - 22 Sep	easyJet
23 Sep - 30 Sep	easyJet
10 Sep - 25 Sep	easyJet
10 Sep - 17 Sep	easyJet
17 Sep - 27 Sep	easyJet
22 Sep - 23 Sep	easyJet
20 Sep - 05 Oct	easyJet
20 Sep - 04 Oct	easyJet
21 Sep - 04 Oct	easyJet
27 Sep - 11 Oct	easyJet
28 Sep - 04 Oct	easyJet
28 Sep - 12 Oct	easyJet
24 Sep - 01 Oct	Vueling Airlines
16 Sep - 07 Oct	Vueling Airlines
24 Sep - 02 Oct	Vueling Airlines

Also check the deals for one-way flights from Lisbon to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Istanbul in September from $199

Return flights