AirHint found the following cheapest return flights from Lisbon (LIS) to Santiago (SCL) in September 2025 (see full year).

Return flights

10 Sep - 19 Sep	Air France
09 Sep - 17 Sep	Air France
09 Sep - 18 Sep	Air France
15 Sep - 25 Sep	Air France
14 Sep - 29 Sep	Air France
15 Sep - 01 Oct	Air France
11 Sep - 24 Sep	Air France
16 Sep - 01 Oct	Air France
23 Sep - 11 Oct	TAP
16 Sep - 23 Sep	Air France
16 Sep - 26 Sep	Ryanair
14 Sep - 26 Sep	Air France
23 Sep - 17 Oct	TAP
17 Sep - 26 Sep	Azul Airlines
30 Sep - 29 Oct	TAP
22 Sep - 02 Oct	TAP
30 Sep - 30 Oct	TAP

Also check the deals for one-way flights from Lisbon to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Santiago in September from $1000

Return flights