AirHint found the following cheapest return flights from Lisbon (LIS) to Sao Tome (TMS) in November 2025 (see full year).

Return flights

11 Nov - 17 Nov	TAAG Angola Airlines
13 Nov - 19 Nov	TAAG Angola Airlines
25 Nov - 08 Dec	TAAG Angola Airlines
02 Nov - 14 Nov	TAAG Angola Airlines
08 Nov - 14 Nov	TAP
15 Nov - 30 Nov	TAP
16 Nov - 22 Nov	TAP
22 Nov - 29 Nov	TAP	direct
05 Nov - 12 Nov	TAP
15 Nov - 29 Nov	TAP	direct
15 Nov - 22 Nov	TAP	direct
22 Nov - 08 Dec	TAP
23 Nov - 08 Dec	TAP
28 Nov - 08 Dec	TAP
28 Nov - 01 Dec	TAP
29 Nov - 08 Dec	Euroatlantic Airways Charter
29 Nov - 10 Dec	Euroatlantic Airways Charter
22 Nov - 07 Dec	TAP
30 Nov - 07 Dec	TAP
22 Nov - 06 Dec	TAP	direct

Also check the deals for one-way flights from Lisbon to Sao Tome in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Lisbon to Sao Tome in November from $541

Return flights