AirHint found the following cheapest return flights from London (LON) to Santiago (SCL) in September 2025 (see full year).

Return flights

17 Sep - 15 Oct	easyJet
30 Sep - 18 Oct	Ryanair
27 Sep - 07 Oct	Norse Atlantic Airways (UK)
22 Sep - 29 Sep	easyJet
27 Sep - 30 Sep	Norse Atlantic Airways (UK)
18 Sep - 25 Sep	easyJet
22 Sep - 03 Oct	Norse Atlantic Airways (UK)
26 Sep - 06 Oct	Norse Atlantic Airways (UK)
26 Sep - 30 Sep	Norse Atlantic Airways (UK)
25 Sep - 03 Oct	easyJet
23 Sep - 04 Oct	Vueling Airlines
16 Sep - 21 Sep	Ryanair
18 Sep - 02 Oct	Ryanair
27 Sep - 04 Oct	Norse Atlantic Airways (UK)
28 Sep - 05 Oct	Avianca
20 Sep - 28 Sep	Vueling Airlines
20 Sep - 27 Sep	Ryanair
16 Sep - 26 Sep	LATAM Airlines Group
30 Sep - 30 Sep	Ryanair
19 Sep - 19 Sep	Ryanair

Also check the deals for one-way flights from London to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in September from $1040

Return flights