AirHint found the following cheapest return flights from London (LTN) to Santiago (SCL) in September 2025 (see full year).

Return flights

01 Sep - 19 Sep	easyJet
01 Sep - 30 Sep	Ryanair
11 Sep - 25 Sep	Ryanair
17 Sep - 24 Sep	easyJet
26 Sep - 29 Sep	easyJet
01 Sep - 15 Sep	Ryanair
17 Sep - 15 Oct	easyJet
10 Sep - 17 Sep	easyJet
04 Sep - 19 Sep	Ryanair
20 Sep - 04 Oct	easyJet
18 Sep - 06 Oct	easyJet
08 Sep - 07 Oct	easyJet
20 Sep - 11 Oct	easyJet
08 Sep - 23 Sep	Ryanair
12 Sep - 19 Sep	easyJet
25 Sep - 02 Oct	Ryanair
24 Sep - 01 Oct	easyJet
29 Sep - 06 Oct	easyJet
19 Sep - 06 Oct	easyJet
30 Sep - 25 Oct	easyJet

Also check the deals for one-way flights from London to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in September from $1122

Return flights