AirHint found the following cheapest return flights from Luxemburg (LUX) to Prague (PRG) in October 2025 (see full year).

Return flights

09 Oct - 16 Oct	Ryanair
16 Oct - 16 Nov	Ryanair
14 Oct - 16 Oct	Ryanair
15 Oct - 17 Oct	Luxair	direct
24 Oct - 31 Oct	Luxair	direct
06 Oct - 08 Oct	Luxair	direct
12 Oct - 15 Oct	Luxair	direct
05 Oct - 08 Oct	Luxair	direct
10 Oct - 17 Oct	Ryanair
15 Oct - 18 Oct	Ryanair
17 Oct - 20 Oct	Ryanair
17 Oct - 17 Nov	Ryanair
31 Oct - 03 Nov	Ryanair
17 Oct - 17 Nov	Luxair	direct

Also check the deals for one-way flights from Luxemburg to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Luxemburg to Prague in October from $130

Return flights