AirHint found the following cheapest return flights from Luxemburg (LUX) to Prague (PRG) in September 2025 (see full year).

Return flights

15 Sep - 19 Sep	Luxair	direct
24 Sep - 29 Sep	Luxair	direct
28 Sep - 01 Oct	Luxair	direct
29 Sep - 03 Oct	Luxair	direct
03 Sep - 05 Sep	Ryanair
22 Sep - 25 Sep	easyJet
23 Sep - 26 Sep	KLM
12 Sep - 15 Sep	Ryanair
14 Sep - 15 Sep	Ryanair
08 Sep - 08 Sep	KLM
23 Sep - 28 Sep	Lufthansa
03 Sep - 08 Sep	KLM

Also check the deals for one-way flights from Luxemburg to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Luxemburg to Prague in September from $150

Return flights