AirHint found the following cheapest return flights from Madrid (MAD) to Cairo (CAI) in December 2025 (see full year).

Return flights

08 Dec - 18 Dec	Iberia Express	direct
08 Dec - 13 Dec	Iberia Express	direct
08 Dec - 22 Dec	Iberia Express	direct
06 Dec - 13 Dec	Iberia	direct
10 Dec - 15 Jan	Wizz Air Malta
11 Dec - 18 Dec	Wizz Air Malta
11 Dec - 15 Dec	Wizz Air Malta
12 Dec - 18 Dec	Wizz Air Malta
08 Dec - 15 Dec	Iberia Express
13 Dec - 18 Dec	Iberia
10 Dec - 17 Dec	Wizz Air Malta
30 Dec - 10 Jan	SWISS
27 Dec - 11 Jan	SWISS
13 Dec - 10 Jan	Iberia
30 Dec - 11 Jan	SWISS
30 Dec - 18 Jan	SWISS
15 Dec - 12 Jan	Ryanair
30 Dec - 05 Jan	SWISS
27 Dec - 05 Jan	SWISS
30 Dec - 07 Jan	SWISS

Also check the deals for one-way flights from Madrid to Cairo in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Cairo in December from $221

Return flights