AirHint found the following cheapest return flights from Madrid (MAD) to Cairo (CAI) in September 2025 (see full year).

Return flights

29 Sep - 10 Oct	Wizz Air Malta
07 Sep - 19 Sep	Iberia
16 Sep - 19 Sep	Iberia
24 Sep - 03 Oct	Wizz Air Malta
10 Sep - 19 Sep	Wizz Air Malta
23 Sep - 01 Oct	Wizz Air Malta
13 Sep - 19 Sep	Ryanair
29 Sep - 07 Oct	Wizz Air Malta
22 Sep - 03 Oct	Wizz Air Malta
18 Sep - 03 Oct	Wizz Air Malta
12 Sep - 19 Sep	Ryanair
24 Sep - 01 Oct	Wizz Air Malta
07 Sep - 17 Sep	Iberia
24 Sep - 29 Sep	Wizz Air Malta
22 Sep - 01 Oct	Wizz Air Malta
09 Sep - 19 Sep	Ryanair
15 Sep - 19 Sep	Wizz Air Malta
16 Sep - 21 Sep	Wizz Air Malta
23 Sep - 02 Oct	Wizz Air Malta
17 Sep - 08 Oct	ITA Airways

Also check the deals for one-way flights from Madrid to Cairo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Cairo in September from $264

Return flights