AirHint found the following cheapest return flights from Madrid (MAD) to Guatemala City (GUA) in October 2025 (see full year).

Return flights

09 Oct - 31 Oct	Lufthansa
06 Oct - 19 Oct	Air Canada
08 Oct - 20 Oct	United
15 Oct - 29 Oct	United
15 Oct - 30 Oct	United
02 Oct - 16 Oct	United
30 Oct - 26 Nov	United
14 Oct - 28 Oct	Brussels Airlines
07 Oct - 21 Oct	United
30 Oct - 09 Nov	United
29 Oct - 18 Nov	United
28 Oct - 18 Nov	Brussels Airlines
29 Oct - 26 Nov	United
24 Oct - 09 Nov	United
06 Oct - 18 Oct	United
06 Oct - 12 Oct	Ryanair
31 Oct - 08 Nov	TAP
31 Oct - 15 Nov	TAP
31 Oct - 21 Nov	Ryanair
25 Oct - 08 Nov	TAP

Also check the deals for one-way flights from Madrid to Guatemala City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Guatemala City in October from $561

Return flights