AirHint found the following cheapest return flights from Madrid (MAD) to Guatemala City (GUA) in December 2025 (see full year).

Return flights

03 Dec - 11 Dec	Air Europa
03 Dec - 10 Dec	Air Europa
05 Dec - 11 Dec	Ryanair
04 Dec - 10 Dec	Ryanair
03 Dec - 14 Dec	Air Europa
27 Dec - 23 Jan	TAP
05 Dec - 12 Dec	Ryanair
03 Dec - 07 Dec	Air Europa
10 Dec - 08 Jan	Air Europa
10 Dec - 10 Jan	Air Europa
06 Dec - 09 Dec	TAP
05 Dec - 10 Dec	Ryanair
04 Dec - 07 Dec	United
08 Dec - 12 Jan	United
09 Dec - 12 Jan	United
16 Dec - 17 Jan	Air Europa
15 Dec - 17 Jan	United
15 Dec - 12 Jan	United
10 Dec - 01 Jan	Air Europa
13 Dec - 11 Jan	Air Europa

Also check the deals for one-way flights from Madrid to Guatemala City in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Guatemala City in December from $787

Return flights