AirHint found the following cheapest return flights from Madrid (MAD) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

30 Dec - 24 Jan	Avianca
28 Dec - 28 Jan	Avianca
14 Dec - 31 Dec	LATAM Airlines Group
24 Dec - 16 Jan	Avianca
14 Dec - 28 Dec	Avianca
15 Dec - 25 Jan	Avianca
24 Dec - 02 Jan	Avianca
13 Dec - 30 Dec	Avianca
13 Dec - 27 Dec	Avianca
14 Dec - 27 Dec	Avianca
26 Dec - 11 Jan	Avianca
12 Dec - 31 Dec	Avianca
29 Dec - 11 Jan	Avianca
22 Dec - 29 Dec	Avianca
22 Dec - 24 Jan	Avianca
15 Dec - 15 Dec	Avianca
21 Dec - 29 Jan	Avianca
21 Dec - 28 Jan	Avianca
19 Dec - 29 Dec	Avianca
22 Dec - 31 Dec	Avianca

Also check the deals for one-way flights from Madrid to Guayaquil in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Guayaquil in December from $952

Return flights