AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (IST) in June 2026 (see full year).

Return flights

05 Jun - 13 Jun	Aegean Airlines
01 Jun - 04 Jun	Aegean Airlines
12 Jun - 14 Jun	Aegean Airlines
01 Jun - 22 Jun	Aegean Airlines
07 Jun - 11 Jun	Aegean Airlines
02 Jun - 05 Jun	Wizz Air
10 Jun - 16 Jun	Iberia Express
20 Jun - 27 Jun	Aegean Airlines
02 Jun - 05 Jun	Air Europa	direct
26 Jun - 03 Jul	Aegean Airlines
01 Jun - 04 Jun	Air Europa	direct
26 Jun - 03 Jul	Air Europa	direct
30 Jun - 04 Jul	Air Europa	direct

Also check the deals for one-way flights from Madrid to Istanbul in June.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Istanbul in June from $244

Return flights