AirHint found the following cheapest return flights from Madrid (MAD) to Osaka (KIX) in September 2025 (see full year).

Return flights

04 Sep - 16 Sep	Etihad Airways
17 Sep - 28 Sep	Wizz Air Malta
22 Sep - 21 Oct	China Eastern
17 Sep - 16 Oct	Iberia
06 Sep - 21 Sep	Etihad Airways
02 Sep - 16 Sep	Hainan Airlines
23 Sep - 07 Oct	Ryanair
13 Sep - 28 Sep	KLM
05 Sep - 14 Sep	Air France
02 Sep - 17 Sep	Hainan Airlines
22 Sep - 07 Oct	Sichuan Airlines
03 Sep - 16 Sep	Etihad Airways
11 Sep - 22 Sep	Lufthansa
09 Sep - 23 Sep	Ryanair
29 Sep - 07 Oct	Sichuan Airlines
20 Sep - 18 Oct	Ryanair
27 Sep - 07 Oct	Wizz Air Malta
15 Sep - 13 Oct	Ryanair
28 Sep - 07 Oct	Sichuan Airlines
25 Sep - 12 Oct	Hainan Airlines

Also check the deals for one-way flights from Madrid to Osaka in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Osaka in September from $728

Return flights