AirHint found the following cheapest return flights from Madrid (MAD) to Osaka (KIX) in September 2025 (see full year).

Return flights

24 Sep - 22 Oct	Air China
24 Sep - 15 Oct	Air China
26 Sep - 18 Oct	Air China
28 Sep - 14 Oct	Air China
27 Sep - 24 Oct	Air China
24 Sep - 07 Oct	Air China
24 Sep - 11 Oct	China Eastern
25 Sep - 12 Oct	Air China
28 Sep - 12 Oct	Air China
22 Sep - 21 Oct	Sichuan Airlines
23 Sep - 30 Sep	Hainan Airlines
22 Sep - 29 Sep	Sichuan Airlines
20 Sep - 22 Sep	Air China
21 Sep - 30 Sep	Hainan Airlines
22 Sep - 30 Sep	Sichuan Airlines
19 Sep - 26 Sep	Beijing Capital Airlines
19 Sep - 21 Sep	Beijing Capital Airlines
20 Sep - 21 Sep	Hainan Airlines

Also check the deals for one-way flights from Madrid to Osaka in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Osaka

Cheap car rent in Osaka

Cheapest return flights from Madrid to Osaka in September from $712

Return flights