AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in March 2026 (see full year).

Return flights

04 Mar - 15 Mar	Avianca
01 Mar - 13 Mar	Avianca
01 Mar - 12 Mar	Avianca
11 Mar - 25 Mar	United
11 Mar - 21 Mar	Iberia	direct
11 Mar - 25 Mar	Iberia	direct
21 Mar - 05 Apr	KLM
27 Mar - 05 Apr	Air France
26 Mar - 07 Apr	United
26 Mar - 03 Apr	United
11 Mar - 27 Mar	KLM
11 Mar - 26 Mar	Air Europa	direct
05 Mar - 22 Mar	Air Europa	direct
01 Mar - 12 Mar	Air Europa	direct
25 Mar - 01 Apr	KLM
26 Mar - 06 Apr	KLM
26 Mar - 04 Apr	Air Europa	direct
27 Mar - 12 Apr	United
25 Mar - 01 Apr	Air Europa	direct
26 Mar - 03 Apr	Air Europa	direct

Also check the deals for one-way flights from Madrid to Panama City in March.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Panama City in March from $625

Return flights