Cheapest return flights from Madrid to Panama City in May from $652

Best time to book flights for Madrid (MAD) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from Madrid (MAD) to Panama City (PTY) in May 2025 (see full year).

Return flights

13 May - 26 May United
27 May - 14 Jun KLM
12 May - 26 May United
19 May - 26 May United
20 May - 27 May United
16 May - 26 May United
26 May - 03 Jun Air France
30 May - 10 Jun United
28 May - 03 Jun KLM
25 May - 04 Jun KLM
30 May - 09 Jun Air France
24 May - 07 Jun Air Europa direct
16 May - 27 May United
23 May - 07 Jun United
30 May - 07 Jun United
30 May - 09 Jun Iberia direct
16 May - 23 May Iberia direct
19 May - 23 May Iberia direct
26 May - 30 May Iberia direct
19 May - 26 May Iberia direct

Also check the deals for one-way flights from Madrid to Panama City in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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