AirHint found the following cheapest return flights from Madrid (MAD) to Istanbul (SAW) in September 2025 (see full year).

Return flights

17 Sep - 24 Sep	Wizz Air Malta
16 Sep - 23 Sep	Wizz Air Malta
24 Sep - 30 Sep	Wizz Air Malta
23 Sep - 30 Sep	Wizz Air Malta
25 Sep - 30 Sep	Wizz Air Malta
23 Sep - 28 Sep	Wizz Air Malta
24 Sep - 27 Sep	Wizz Air Malta
25 Sep - 09 Oct	Wizz Air Malta
25 Sep - 06 Oct	Wizz Air Malta
25 Sep - 02 Oct	Wizz Air Malta
18 Sep - 09 Oct	Wizz Air Malta
15 Sep - 29 Sep	Wizz Air Malta
23 Sep - 01 Oct	Wizz Air Malta
16 Sep - 21 Sep	Wizz Air Malta
21 Sep - 28 Sep	Wizz Air Malta
25 Sep - 05 Oct	Wizz Air Malta
10 Sep - 07 Oct	Ryanair
26 Sep - 05 Oct	Ryanair
20 Sep - 04 Oct	Ryanair
26 Sep - 12 Oct	Ryanair

Also check the deals for one-way flights from Madrid to Istanbul in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Istanbul in September from $179

Return flights