AirHint found the following cheapest return flights from Madrid (MAD) to Santiago (SCL) in November 2025 (see full year).

Return flights

06 Nov - 17 Nov	Delta
13 Nov - 26 Nov	Delta
13 Nov - 27 Nov	Delta
12 Nov - 27 Nov	Delta
12 Nov - 18 Nov	Delta
06 Nov - 27 Nov	Delta
12 Nov - 26 Nov	Delta
06 Nov - 14 Nov	Delta
12 Nov - 23 Nov	Delta
24 Nov - 03 Dec	Delta
27 Nov - 09 Dec	Delta
27 Nov - 05 Dec	Delta
24 Nov - 05 Dec	Delta
23 Nov - 05 Dec	Delta
24 Nov - 08 Dec	Delta
27 Nov - 08 Dec	Delta
12 Nov - 04 Dec	Delta
24 Nov - 04 Dec	Delta
23 Nov - 08 Dec	Delta
13 Nov - 23 Nov	Delta

Also check the deals for one-way flights from Madrid to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Santiago in November from $816

Return flights