AirHint found the following cheapest return flights from Madrid (MAD) to Quito (UIO) in December 2025 (see full year).

Return flights

03 Dec - 10 Dec	Iberia
03 Dec - 15 Dec	Iberia
01 Dec - 15 Dec	Iberia
01 Dec - 23 Dec	Iberia
03 Dec - 14 Dec	Iberia
03 Dec - 18 Dec	Iberia
31 Dec - 19 Jan	Iberia
04 Dec - 15 Dec	Iberia
02 Dec - 09 Dec	Avianca
04 Dec - 14 Dec	Iberia
01 Dec - 28 Dec	Iberia
01 Dec - 01 Jan	Iberia
01 Dec - 17 Jan	Iberia
09 Dec - 20 Jan	American Airlines
26 Dec - 16 Jan	Avianca
10 Dec - 29 Jan	Ryanair
02 Dec - 26 Jan	Iberia
31 Dec - 18 Jan	Avianca
14 Dec - 25 Jan	Avianca
15 Dec - 12 Jan	Wizz Air Malta

Also check the deals for one-way flights from Madrid to Quito in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Quito in December from $858

Return flights