AirHint found the following cheapest return flights from Madrid (MAD) to Quito (UIO) in April 2026 (see full year).

Return flights

01 Apr - 22 Apr	LATAM Airlines Group	direct
01 Apr - 25 Apr	LATAM Airlines Group
01 Apr - 20 Apr	LATAM Airlines Group
13 Apr - 27 Apr	LATAM Airlines Group
02 Apr - 19 Apr	Avianca
01 Apr - 20 Apr	Iberia	direct
01 Apr - 25 Apr	Iberia	direct
01 Apr - 10 Apr	Iberia	direct
02 Apr - 19 Apr	LATAM Airlines Group	direct
01 Apr - 06 Apr	KLM

Also check the deals for one-way flights from Madrid to Quito in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Quito in April from $820

Return flights