AirHint found the following cheapest return flights from Madrid (MAD) to Quito (UIO) in September 2025 (see full year).

Return flights

09 Sep - 26 Sep	Delta
08 Sep - 21 Sep	Delta
12 Sep - 21 Sep	Delta
04 Sep - 21 Sep	Delta
11 Sep - 28 Sep	Delta
15 Sep - 28 Sep	Delta
12 Sep - 28 Sep	Delta
15 Sep - 06 Oct	Delta
25 Sep - 21 Oct	Delta
08 Sep - 19 Oct	Delta
15 Sep - 15 Oct	Delta
04 Sep - 14 Sep	Delta
03 Sep - 22 Sep	Delta
11 Sep - 14 Sep	Delta
25 Sep - 02 Oct	Delta
16 Sep - 02 Oct	Delta
23 Sep - 07 Oct	Delta
07 Sep - 20 Oct	Delta
22 Sep - 14 Oct	Avianca
13 Sep - 04 Oct	Avianca

Also check the deals for one-way flights from Madrid to Quito in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Madrid to Quito in September from $790

Return flights