AirHint found the following cheapest return flights from Manchester (MAN) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

12 Sep - 29 Sep	KLM
18 Sep - 08 Oct	Air France
11 Sep - 17 Oct	KLM
01 Sep - 01 Oct	Air France
01 Sep - 22 Sep	Air France
09 Sep - 15 Sep	Ryanair
06 Sep - 19 Sep	Delta
22 Sep - 28 Sep	Delta
08 Sep - 21 Sep	Delta
01 Sep - 21 Sep	Delta
01 Sep - 07 Sep	Delta
03 Sep - 28 Sep	Delta
10 Sep - 17 Sep	Delta
27 Sep - 14 Oct	Delta
12 Sep - 05 Oct	Lufthansa

Also check the deals for one-way flights from Manchester to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Sao Paulo

Cheap car rent in Sao Paulo

Cheapest return flights from Manchester to Sao Paulo in September from $857

Return flights