AirHint found the following cheapest return flights from Manchester (MAN) to Karachi (KHI) in September 2025 (see full year).

Return flights

03 Sep - 27 Sep	Ryanair
14 Sep - 25 Sep	Ryanair
05 Sep - 19 Sep	Ryanair
18 Sep - 11 Oct	Ryanair
18 Sep - 12 Oct	Ryanair
11 Sep - 26 Sep	Ryanair
18 Sep - 09 Oct	Ryanair
09 Sep - 25 Sep	Ryanair
08 Sep - 19 Sep	Ryanair
11 Sep - 28 Sep	Ryanair
10 Sep - 25 Sep	Ryanair
14 Sep - 21 Sep	Ryanair
05 Sep - 27 Sep	Ryanair
25 Sep - 02 Oct	Ryanair
23 Sep - 14 Oct	easyJet
26 Sep - 14 Oct	Ryanair
26 Sep - 23 Oct	Ryanair
26 Sep - 24 Oct	Ryanair
30 Sep - 14 Oct	Ryanair
30 Sep - 21 Oct	Ryanair

Also check the deals for one-way flights from Manchester to Karachi in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Manchester to Karachi in September from $477

Return flights