AirHint found the following cheapest return flights from Manaus (MAO) to Madrid (MAD) in October 2025 (see full year).

Return flights

20 Oct - 02 Nov	Avianca
20 Oct - 04 Nov	TAP
18 Oct - 27 Oct	Avianca
19 Oct - 27 Oct	Avianca
17 Oct - 27 Oct	Avianca
16 Oct - 27 Oct	Avianca
20 Oct - 27 Oct	Avianca
20 Oct - 31 Oct	Avianca
20 Oct - 28 Oct	TAP
20 Oct - 29 Oct	Avianca
21 Oct - 26 Oct	Avianca
19 Oct - 25 Oct	Avianca
21 Oct - 05 Nov	Avianca
20 Oct - 01 Nov	Avianca
21 Oct - 04 Nov	GOL Linhas Aéreas
20 Oct - 03 Nov	TAP
19 Oct - 04 Nov	Air Europa

Also check the deals for one-way flights from Manaus to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Manaus to Madrid in October from $886

Return flights