AirHint found the following cheapest return flights from Orlando (MCO) to Panama City (PTY) in November 2025 (see full year).

Return flights

15 Nov - 22 Nov	Volaris Costa Rica
20 Nov - 24 Nov	Spirit Airlines
18 Nov - 02 Dec	Volaris Costa Rica
28 Nov - 12 Dec	Volaris Costa Rica
16 Nov - 23 Nov	Avianca
13 Nov - 22 Nov	Avianca
22 Nov - 29 Nov	Spirit Airlines
14 Nov - 22 Nov	Volaris Costa Rica
28 Nov - 12 Dec	Copa	direct
18 Nov - 02 Dec	Copa	direct
16 Nov - 23 Nov	Copa	direct
14 Nov - 22 Nov	Copa	direct
15 Nov - 22 Nov	Copa	direct
13 Nov - 22 Nov	Copa	direct

Also check the deals for one-way flights from Orlando to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Orlando to Panama City in November from $388

Return flights