Cheapest return flights from Rio Negro to Sao Paulo in October from $382

AirHint found the following cheapest return flights from Rio Negro (MDE) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

24 Oct - 27 Oct Copa
14 Oct - 21 Oct Copa
22 Oct - 27 Oct Copa
14 Oct - 18 Oct Copa
15 Oct - 22 Oct Copa
22 Oct - 25 Oct Copa
03 Oct - 07 Oct LATAM Airlines Group
02 Oct - 06 Oct Copa
16 Oct - 01 Nov LATAM Airlines Group
09 Oct - 12 Oct Avianca
04 Oct - 11 Oct Avianca

Also check the deals for one-way flights from Rio Negro to Sao Paulo in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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