Cheapest return flights from Rio Negro to Sao Paulo in September from $418

AirHint found the following cheapest return flights from Rio Negro (MDE) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

25 Sep - 02 Oct Copa
24 Sep - 01 Oct Copa
25 Sep - 28 Sep Avianca
23 Sep - 30 Sep Copa
24 Sep - 29 Sep Avianca
24 Sep - 03 Oct Avianca
23 Sep - 27 Sep JetSmart
23 Sep - 29 Sep JetSmart
27 Sep - 11 Oct Avianca
22 Sep - 26 Sep JetSmart
22 Sep - 30 Sep JetSmart

Also check the deals for one-way flights from Rio Negro to Sao Paulo in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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