Cheapest return flights from Rio Negro to Guatemala City in December from $299

AirHint found the following cheapest return flights from Rio Negro (MDE) to Guatemala City (GUA) in December 2025 (see full year).

Return flights

06 Dec - 08 Dec Arajet
24 Dec - 28 Dec Copa
24 Dec - 04 Jan Copa
05 Dec - 10 Dec LATAM Airlines Group
05 Dec - 08 Dec Avianca
04 Dec - 10 Dec JetSmart
22 Dec - 04 Jan Copa
07 Dec - 12 Dec Copa
22 Dec - 05 Jan Copa
17 Dec - 27 Dec Avianca
22 Dec - 02 Jan Copa
09 Dec - 17 Dec JetSmart
08 Dec - 11 Dec Avianca
08 Dec - 12 Dec Avianca
20 Dec - 03 Jan Avianca

Also check the deals for one-way flights from Rio Negro to Guatemala City in December.

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