Cheapest return flights from Rio Negro to Madrid in October from $651

AirHint found the following cheapest return flights from Rio Negro (MDE) to Madrid (MAD) in October 2025 (see full year).

Return flights

22 Oct - 29 Oct Spirit Airlines
24 Oct - 07 Nov Spirit Airlines
04 Oct - 14 Oct Spirit Airlines
07 Oct - 23 Oct Spirit Airlines
07 Oct - 14 Oct Spirit Airlines
12 Oct - 24 Oct Spirit Airlines
19 Oct - 15 Nov Avianca
30 Oct - 03 Nov Spirit Airlines
07 Oct - 24 Nov Spirit Airlines
07 Oct - 23 Nov Spirit Airlines
18 Oct - 23 Nov Spirit Airlines
15 Oct - 06 Nov Spirit Airlines
19 Oct - 28 Oct Spirit Airlines
17 Oct - 14 Nov Avianca
24 Oct - 10 Nov Avianca direct
31 Oct - 18 Nov Spirit Airlines
11 Oct - 26 Oct JetSmart
21 Oct - 25 Oct Copa
08 Oct - 23 Oct Spirit Airlines
16 Oct - 23 Oct Spirit Airlines

Also check the deals for one-way flights from Rio Negro to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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