AirHint found the following cheapest return flights from Rio Negro (MDE) to Madrid (MAD) in November 2025 (see full year).

Return flights

14 Nov - 26 Nov	Spirit Airlines
07 Nov - 27 Nov	Avianca
03 Nov - 13 Nov	Spirit Airlines
03 Nov - 17 Nov	Avianca	direct
25 Nov - 07 Dec	Arajet
02 Nov - 15 Nov	Spirit Airlines
05 Nov - 12 Nov	Spirit Airlines
23 Nov - 07 Dec	Arajet
07 Nov - 14 Nov	Copa
06 Nov - 19 Nov	Spirit Airlines
06 Nov - 21 Nov	Spirit Airlines
13 Nov - 01 Dec	Spirit Airlines
10 Nov - 24 Nov	Avianca	direct
25 Nov - 06 Dec	Arajet
27 Nov - 06 Dec	Avianca
30 Nov - 07 Dec	Copa
30 Nov - 31 Dec	Air Europa	direct
25 Nov - 30 Dec	Arajet
22 Nov - 06 Dec	Avianca
25 Nov - 13 Dec	Arajet

Also check the deals for one-way flights from Rio Negro to Madrid in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Madrid in November from $756

Return flights