AirHint found the following cheapest return flights from Rio Negro (MDE) to Santiago (SCL) in August 2025 (see full year).

Return flights

25 Aug - 01 Sep	JetSmart
25 Aug - 07 Sep	JetSmart
21 Aug - 25 Aug	JetSmart
25 Aug - 08 Sep	JetSmart
31 Aug - 19 Sep	JetSmart
21 Aug - 01 Sep	JetSmart
21 Aug - 07 Sep	JetSmart
21 Aug - 08 Sep	JetSmart
25 Aug - 10 Sep	JetSmart
21 Aug - 26 Aug	JetSmart
31 Aug - 01 Sep	JetSmart
25 Aug - 04 Sep	JetSmart
22 Aug - 25 Aug	JetSmart
17 Aug - 25 Aug	JetSmart
06 Aug - 25 Aug	JetSmart
12 Aug - 25 Aug	JetSmart
07 Aug - 14 Aug	LATAM Airlines Group
20 Aug - 25 Aug	JetSmart
13 Aug - 25 Aug	JetSmart
14 Aug - 25 Aug	JetSmart

Also check the deals for one-way flights from Rio Negro to Santiago in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rio Negro to Santiago in August from $331

Return flights